Salesforce Expands Agentic AI With Anthropic Collaboration

Salesforce (NYSE: CRM) has partnered with Anthropic (private: ANTHRO) to integrate Claude models into its Agentforce 360 AI platform, providing enterprise-grade AI capabilities tailored for regulated and data-sensitive industries such as finance, healthcare, life sciences, and cybersecurity.

The collaboration aims to make agentic AI — autonomous, workflow-driven AI that can reason and act on complex tasks — available within Salesforce’s enterprise ecosystem, improving customer service, compliance workflows, and operational efficiency.

Claude Integration Across Salesforce Ecosystem

Claude is being positioned as a preferred model for high-trust environments within Salesforce’s suite. It is also being embedded into Slack, offering conversational AI capabilities to enhance productivity and communication across organizations.

“By bringing Salesforce directly into Claude — and Claude’s intelligence into Salesforce and Slack — we’re giving every company the power to work in entirely new ways,” said Marc Benioff, CEO of Salesforce.
“Together, we’re making trusted, agentic AI real for every industry — combining Anthropic’s world-class models with the trust, reliability, accuracy and scale of Agentforce 360.”

Dario Amodei, CEO and co-founder of Anthropic, added that the partnership balances innovation with safety:

“Regulated industries need frontier AI capabilities, but they also need safeguards before deploying in sensitive systems. Claude delivers both — performance and protection.”

Expanding AI Collaboration Network

In addition to the Anthropic deal, Salesforce also announced a new collaboration with OpenAI (OPENAI) to enhance Agentforce 360’s multi-model AI integration, allowing enterprises to choose from top-tier LLMs including Claude and GPT-based models.

Salesforce’s multi-model approach aims to empower customers with flexibility, ensuring compliance while delivering cutting-edge automation across customer engagement, data analysis, and workflow orchestration.